►个人简介
张白曦,威尼斯432888can副研究员、硕士生导师,2013年入职威尼斯432888can,主要研究领域为食品生物技术。主持并参与多项国家自然科学基金、江苏省自然科学基金等研究项目,已发表学术论文二十余篇,授权国家发明专利六项。
►教育背景
博士,(专业),(毕业学校),食品科学,威尼斯432888can;
硕士,(专业),(毕业学校)
学士,(专业),(毕业学校),食品科学与工程,威尼斯432888can。
►研究方向
功能食品原料的挖掘及绿色制造
1.国家自然科学基金青年项目(31501457)2016—2018;
2.江苏省自然科学基金青年项目(BK20150144)2015—2018;
3.蓝靛果果渣缓解结肠炎的功能评价及机制研究(企业技术服务)
4.紫苏籽油对高血脂患者脂代谢的调节作用及机制研究(企业技术服务)
5.桦南地方特色食品研究与开发(企业技术服务)
1.Baixi Zhang*, Jiancan Cao, Improving and Streamlining Gene Editing in Yarrowia lipolytica via Integration of Engineered Cas9 Protein, Journal of Fungi, 2024,10(1):63.
2.Baixi Zhang*, Lijuan Niu, Xinwen Huang, Lonicera Caerulea Juice Alleviates Alcoholic Liver Disease by Regulating Intestinal Flora and the FXR-FGF15 Signaling Pathway, Nutrients, 2023,15(18): 4025.
3.Baixi Zhang*,Xinwen Huang, Lijuan Niu, Xuemei Chen, Bo Hu, Xiaoshu Tang, Lonicera caerulea Pomace Alleviates DSS-Induced Colitis via Intestinal Barrier Improvement and Gut Microbiota Modulation, Foods, 2023,12(18): 3329.
4.Baixi Zhang*, Lijuan Ni, Xiaoshu Tang, Xuemei, Chen, Bo Hu, Engineering the beta-Oxidation Pathway in Yarrowia lipolytica for the Production of trans-10, cis-12-Conjugated Linoleic Acid, Journal of Agricultural and Food Chemistry, 2022,70(27): 8377-8384.
5.Baixi Zhang*,Tong Zhu, Xintian Huang, Enhanced Soluble Expression of Linoleic Acid Isomerase by Coordinated Regulation of Promoter and Fusion Tag in Escherichia coli, Foods, 2022, 11(10), 1515.
6.Yiwei Yang, Yanping Xia,Baixi Zhang, Dan Li, Jiai Yan, Ju Yang, Jing Sun, Hong Cao, Yingyu Wang*, Feng Zhang*, Effects of different n-6/n-3 polyunsaturated fatty acids ratios on lipid metabolism in patients with hyperlipidemia: a randomized controlled clinical trial, Frontiers in Nutrition, 2023, 10:1166702.
7.Baixi Zhang,Yuhang Song, Haiqin Chen, Hao Zhang, Wei Chen*,Production of trans-10, cis-12-conjugated linoleic acid using permeabilized whole-cell biocatalyst of Yarrowia lipolytica,Biotechnology Letters, 2016. 38(11):1917-1922.
8.张白曦,宋宇航,杨芹,张灏,陈卫*,甲酯化方法对甘油三脂和游离型脂肪酸混合物脂肪酸分析的影响,中国粮油学报,2016,31(9):95-99
9.Baixi Zhang#, Haiqin Chen#, Min Li, Zhennan Gu,Yuanda Song,Colin Ratledge, Yong Q. Chen,Hao Zhang*,Wei Chen*,Geneticengineering ofYarrowia lipolyticafor enhanced production of trans-10,cis-12conjugated linoleic acid, Microbial Cell Factories,2013, 12(70).
10.Baixi Zhang, Chunchi Rong, Haiqin Chen, Yuanda Song, Hao Zhang*, Wei Chen, De novo synthesis of trans-10, cis-12 conjugated linoleic acid in oleaginous yeast Yarrowia lipolytica, Microbial Cell Factories, 2012, 11(51).
1.张白曦,陈卫,宋宇航,陈海琴,赵建新,顾震南,田丰伟,王刚,杨芹,陈永泉,张灏,一种重组解脂亚罗酵母CCFM-JU277-9菌株全细胞催化剂的制备方法。2019,ZL201610396579.7
2.陈卫,李敏,张白曦,陈海琴,赵建新,顾震南,田丰伟,王刚,张灏,陈永泉,一种使用含金属离子培养基生产含有共轭亚油酸的脂肪酸甲酯的方法。2016,ZL201410021562.4
3.陈卫,张白曦,陈海琴,李敏,顾震南,赵建新,张秋香,刘小鸣,赵国忠,张灏,陈永泉,一种使用重组耶氏解脂酵母菌株生产含有共轭亚油酸的脂肪酸甲酯的方法。2015,ZL201410020846.1
4.陈卫,陈海琴,李敏,张白曦,赵建新,顾震南,宋元达,田丰伟,杨芹,陈永泉,张灏,一种采用多次转化发酵法生产含有共轭亚油酸的脂肪酸甲酯的方法。2015,ZL201410020823.0
5.陈卫,张灏,张白曦,李敏,宋元达,陈海琴,赵建新,陈永泉,顾振南,基于基因工程策略优化耶氏解脂酵母重组菌合成共轭亚油酸。2014,ZL201310120175.1
6.张灏,宋元达,张白曦,陈卫,陈海琴,刘晓明,赵建新,一种生产共轭亚油酸的重组酵母菌株及其用途,2013,专利号:ZL201210062130.9